Free Novel Read

In Defense of Food Page 13


  Ome­ga-3s ap­pe­ar to play an im­por­tant ro­le in ne­uro­lo­gi­cal de­ve­lop­ment and pro­ces­sing (the hig­hest con­cent­ra­ti­ons of ome­ga-3s in hu­mans are fo­und in the tis­su­es of the bra­in and the eyes), vi­su­al acu­ity (be­fit­ting the­ir ro­le in pho­tosynt­he­sis), the per­me­abi­lity of cell walls, the me­ta­bo­lism of glu­co­se, and the cal­ming of inf­lam­ma­ti­on. Ome­ga-6s are in­vol­ved in fat sto­ra­ge (which is what they do for the plant), the ri­gi­dity of cell walls, clot­ting, and the inf­lam­ma­ti­on res­pon­se. It helps to think of ome­ga-3s as fle­et and fle­xib­le, ome­ga-6s as sturdy and slow. Be­ca­use the two fatty acids com­pe­te with each ot­her for spa­ce in cell memb­ra­nes and for the at­ten­ti­on of va­ri­o­us enzy­mes, the ra­tio bet­we­en ome­ga-3s and ome­ga-6s, in the di­et and in turn in our tis­su­es, may mat­ter mo­re than the ab­so­lu­te qu­an­tity of eit­her fat. So, too much ome­ga-6 may be just as much a prob­lem as too lit­tle ome­ga-3.

  And that might well be a prob­lem for pe­op­le eating a Wes­tern di­et. As the ba­sis of our di­et has shif­ted from le­aves to se­eds, the ra­tio of ome­ga-6s to ome­ga-3s in our bo­di­es has chan­ged too. The sa­me is true for most of our fo­od ani­mals, which in­dust­ri­al ag­ri­cul­tu­re has ta­ken off the­ir ac­cus­to­med di­et of gre­en plants and put on a ric­her di­et of se­eds. The re­sult has be­en a mar­ked dec­li­ne in the amo­unt of ome­ga-3s in mo­dern me­at, da­iry pro­ducts, and eggs, and an inc­re­ase in the amo­unt of ome­ga-6s. At the sa­me ti­me, mo­dern fo­od pro­duc­ti­on prac­ti­ces ha­ve furt­her di­mi­nis­hed the ome­ga-3s in our di­et. Ome­ga-3s, be­ing less stab­le than ome­ga-6s, spo­il mo­re re­adily, so the fo­od in­dustry, fo­cu­sed on sto­re fo­od, has be­en strongly dis­po­sed aga­inst ome­ga-3s long be­fo­re we even knew what they we­re. (Ome­ga-3s we­ren’t re­cog­ni­zed as es­sen­ti­al to the hu­man di­et un­til the 1980s-so­me ti­me af­ter nut­ri­ti­onism’s blan­ket hos­ti­lity to fat had al­re­ady ta­ken hold.) For ye­ars plant bre­eders ha­ve be­en un­wit­tingly se­lec­ting for plants that pro­du­ce fe­wer ome­ga-3s, be­ca­use such crops don’t spo­il as qu­ickly. (Wild gre­ens li­ke purs­la­ne ha­ve subs­tan­ti­al­ly hig­her le­vels of ome­ga-3s than most do­mes­ti­ca­ted plants.) Al­so, when fo­od ma­kers par­ti­al­ly hydro­ge­na­te oils to ren­der them mo­re stab­le, it is the ome­ga-3s that are eli­mi­na­ted. An exe­cu­ti­ve from Fri­to-Lay told Su­san Al­lport in no un­cer­ta­in terms that be­ca­use of the­ir ten­dency to oxi­di­ze, ome­ga-3s “can­not be used in pro­ces­sed fo­ods.”

  Most of the of­fi­ci­al nut­ri­ti­onal ad­vi­ce we’ve be­en get­ting sin­ce the 1970s has, aga­in un­wit­tingly, hel­ped to push ome­ga-3s out of the di­et and to ele­va­te le­vels of ome­ga-6. Be­si­des de­mo­ni­zing fats in ge­ne­ral, that ad­vi­ce has en­co­ura­ged us to mo­ve from sa­tu­ra­ted fats of ani­mal ori­gin (so­me of which, li­ke but­ter, ac­tu­al­ly con­ta­in res­pec­tab­le amo­unts of ome­ga-3s) to se­ed oils, most of which are much hig­her in ome­ga-6s (corn oil es­pe­ci­al­ly), and even mo­re so af­ter par­ti­al hydro­ge­na­ti­on. The mo­ve from but­ter (and es­pe­ci­al­ly but­ter from pas­tu­red cows) to mar­ga­ri­ne, be­si­des int­ro­du­cing trans fats to the di­et, mar­kedly inc­re­ased ome­ga-6s at the cost of ome­ga-3s.

  Thus wit­ho­ut even re­ali­zing what we we­re do­ing, we dra­ma­ti­cal­ly al­te­red the ra­tio of the­se two es­sen­ti­al fats in our di­et and our bo­di­es, with the re­sult that the ra­tio of ome­ga-6 to ome­ga-3 in the typi­cal Ame­ri­can to­day stands at mo­re than 10 to 1. Be­fo­re the wi­desp­re­ad int­ro­duc­ti­on of se­ed oils at the turn of the last cen­tury, the ra­tio was clo­ser to 3 to 1.

  The pre­ci­se ro­le of the­se li­pids in hu­man he­alth is still not comp­le­tely un­ders­to­od, but so­me re­se­arc­hers are con­vin­ced that the­se his­to­ri­cal­ly low le­vels of ome­ga-3 (or, con­ver­sely, his­to­ri­cal­ly high le­vels of ome­ga-6) be­ar res­pon­si­bi­lity for many of the chro­nic di­se­ases as­so­ci­ated with the Wes­tern di­et, inc­lu­ding he­art di­se­ase and di­abe­tes. Po­pu­la­ti­on stu­di­es sug­gest that ome­ga-3 le­vels in the di­et are strongly cor­re­la­ted with ra­tes of he­art di­se­ase, stro­ke, and mor­ta­lity from all ca­uses.* For examp­le, the Japa­ne­se, who con­su­me lar­ge amo­unts of ome­ga-3s (most of it in fish), ha­ve mar­kedly low ra­tes of car­di­ovas­cu­lar di­se­ase in spi­te of the­ir high ra­tes of smo­king and high blo­od pres­su­re. Ame­ri­cans con­su­me only a third as much ome­ga-3s as the Japa­ne­se and ha­ve ne­arly fo­ur ti­mes the ra­te of de­ath from he­art di­se­ase. But the­re is mo­re than epi­de­mi­ology to link ome­ga-3 le­vels and he­art di­se­ase: Cli­ni­cal stu­di­es ha­ve fo­und that inc­re­asing the ome­ga-3s in one’s di­et may re­du­ce the chan­ces of he­art at­tack by a third.†

  What bi­olo­gi­cal mec­ha­nism co­uld exp­la­in the­se fin­dings? A co­up­le of the­ori­es ha­ve emer­ged. Ome­ga-3s are pre­sent in high con­cent­ra­ti­ons in he­art tis­sue whe­re they se­em to play a ro­le in re­gu­la­ting he­art rhythm and pre­ven­ting fa­tal ar­rhyth­mi­as. Ome­ga-3s al­so dam­pen the inf­lam­ma­ti­on res­pon­se, which ome­ga-6s tend to ex­ci­te. Inf­lam­ma­ti­on is now be­li­eved to play an im­por­tant ro­le in car­di­ovas­cu­lar di­se­ase as well as in a ran­ge of ot­her di­sor­ders, inc­lu­ding rhe­uma­to­id arth­ri­tis and Alz­he­imer’s. Ome­ga-6s supply the bu­il­ding blocks for a class of pro-inflam­ma­tory mes­sen­ger che­mi­cals in­vol­ved in the body’s ra­pid-res­pon­se re­ac­ti­on to a ran­ge of prob­lems. One of the­se com­po­unds is throm­bo­xa­ne, which en­co­ura­ges blo­od pla­te­lets to ag­gre­ga­te in­to clots. In cont­rast, ome­ga-3s slow the clot­ting res­pon­se, which is pro­bably why po­pu­la­ti­ons with par­ti­cu­larly high le­vels of ome­ga-3s, such as the Inu­it, are pro­ne to ble­eding. (If the­re is a dan­ger to con­su­ming too much ome­ga-3, ble­eding is pro­bably it.)

  The hypot­he­sis that ome­ga-3 might pro­tect aga­inst he­art di­se­ase was ins­pi­red by stu­di­es of Gre­en­land Es­ki­mos, in whom ome­ga-3 con­sump­ti­on is high and he­art di­se­ase ra­re. Es­ki­mos eating the­ir tra­di­ti­onal ma­ri­ne-ba­sed di­et al­so don’t se­em to get di­abe­tes, and so­me re­se­arc­hers be­li­eve it is the ome­ga-3s that pro­tect them. Ad­ding ome­ga-3s to the di­et of rats has be­en shown to pro­tect them aga­inst in­su­lin re­sis­tan­ce. (The sa­me ef­fect has not be­en dup­li­ca­ted in hu­mans, ho­we­ver.) The the­ory is that ome­ga-3s inc­re­ase the per­me­abi­lity of the cell’s memb­ra­nes and its ra­te of me­ta­bo­lism. (Hum­ming­birds ha­ve tons of ome­ga-3s in the­ir cell memb­ra­nes; big mam­mals much less.) A cell with a ra­pid me­ta­bo­lism and per­me­ab­le memb­ra­ne sho­uld res­pond par­ti­cu­larly well to in­su­lin, ab­sor­bing mo­re glu­co­se from the blo­od to me­et its hig­her energy re­qu­ire­ments. That sa­me mec­ha­nism sug­gests that di­ets high in ome­ga-3s might pro­tect aga­inst obe­sity as well.

  So why is it, as Su­san Al­lport wri­tes, that “po­pu­la­ti­ons, when gi­ven the cho­ice, will na­tu­ral­ly drift to­ward fo­ods with les­ser amo­unts of ome­ga-3s”? Be­ca­use a fas­ter me­ta­bo­lism inc­re­ases the ne­ed for fo­od and the­re­fo­re the pos­si­bi­lity of hun­ger, she sug­gests, which is a much less ag­re­e­ab­le con­di­ti­on than be­ing over­we­ight. This might help exp­la­in why so many gro­ups ha­ve adop­ted Wes­tern di­ets as so­on as they get the chan­ce.

  It sho­uld be sa­id that re­se­arc­hers wor­king on ome­ga-3s can so­und a bit li­ke Dr. Ca­sa­ubon in Mid­dle­march, hard at work on his “Key to all Mytho­lo­gi­es.” Li­ke­wi­se, ome­ga-3 re­se­arc­hers se­em to be in pos­ses­si­on of a The­o
ry of Everyt­hing, inc­lu­ding hap­pi­ness. The sa­me po­pu­la­ti­on stu­di­es that ha­ve cor­re­la­ted ome­ga-3 de­fi­ci­ency to car­di­ovas­cu­lar di­se­ase ha­ve al­so fo­und strong cor­re­la­ti­ons bet­we­en fal­ling le­vels of ome­ga-3 in the di­et and ri­sing ra­tes of dep­res­si­on, su­ici­de, and even ho­mi­ci­de. So­me re­se­arc­hers imp­li­ca­te ome­ga-3 de­fi­ci­ency in le­ar­ning di­sa­bi­li­ti­es such as at­ten­ti­on de­fi­cit di­sor­der as well. That ome­ga-3s play an im­por­tant ro­le in men­tal func­ti­on has be­en re­cog­ni­zed sin­ce the 1980s, when it was fo­und that ba­bi­es fed on in­fant for­mu­la sup­ple­men­ted with ome­ga-3s sco­red sig­ni­fi­cantly hig­her on tests of both men­tal de­ve­lop­ment and vi­su­al acu­ity than ba­bi­es re­ce­iving for­mu­la sup­ple­men­ted only with ome­ga-6.

  Co­uld it be that the prob­lem with the Wes­tern di­et is a gross de­fi­ci­ency in this es­sen­ti­al nut­ri­ent? A gro­wing num­ber of re­se­arc­hers ha­ve conc­lu­ded that it is, and they vo­ice frust­ra­ti­on that of­fi­ci­al nut­ri­ti­onal ad­vi­ce has be­en slow to re­cog­ni­ze the prob­lem. To do so, of co­ur­se, wo­uld me­an con­ce­ding the er­ror of past nut­ri­ti­onal ad­vi­ce de­mo­ni­zing fats in ge­ne­ral and pro­mo­ting the switch to se­ed oils high in ome­ga-6. But it se­ems li­kely that so­oner or la­ter the go­vern­ment will es­tab­lish mi­ni­mum da­ily re­qu­ire­ments for ome­ga-3 (se­ve­ral ot­her go­vern­ments al­re­ady ha­ve) and, per­haps in ti­me, doc­tors will ro­uti­nely test us for ome­ga-3 le­vels the way they al­re­ady do for cho­les­te­rol.

  Tho­ugh may­be they sho­uld be tes­ting for ome­ga-6 le­vels as well, be­ca­use it’s pos­sib­le that is the gre­ater prob­lem. Ome­ga-6s exist in a kind of ze­ro-sum re­la­ti­ons­hip with ome­ga-3s, co­un­te­rac­ting most of the po­si­ti­ve ef­fects of ome­ga-3 thro­ug­ho­ut the body. Me­rely ad­ding ome­ga-3s to the di­et-by ta­king sup­ple­ments, say-may not do much go­od un­less we al­so re­du­ce the high le­vels of ome­ga-6s that ha­ve en­te­red the Wes­tern di­et with the ad­vent of pro­ces­sed fo­ods, se­ed oils, and fo­ods from ani­mals ra­ised on gra­in. Ni­ne per­cent of the ca­lo­ri­es in the Ame­ri­can di­et to­day co­me from a sing­le ome­ga-6 fatty acid: li­no­le­ic acid, most of it from soy­be­an oil. So­me nut­ri­ti­on ex­perts think that this is fi­ne: Ome­ga-6s, af­ter all, are es­sen­ti­al fatty acids too, and the­ir ri­se to di­etary pro­mi­nen­ce has pus­hed out sa­tu­ra­ted fats, usu­al­ly tho­ught to be a po­si­ti­ve de­ve­lop­ment. But ot­hers strongly di­sag­ree, con­ten­ding that the unp­re­ce­den­ted pro­por­ti­on of ome­ga-6s in the Wes­tern di­et is cont­ri­bu­ting to the full ran­ge of di­sor­ders in­vol­ving inf­lam­ma­ti­on. Joseph Hib­beln, the re­se­arc­her at the Na­ti­onal Ins­ti­tu­tes of He­alth who con­duc­ted po­pu­la­ti­on stu­di­es cor­re­la­ting ome­ga-3 con­sump­ti­on with everyt­hing from stro­ke to su­ici­de, says that the bil­li­ons we spend on an­ti­inf­lam­ma­tory drugs such as as­pi­rin, ibup­ro­fen, and ace­ta­mi­nop­hen is mo­ney spent to un­do the ef­fects of too much ome­ga-6 in the di­et. He wri­tes, “The inc­re­ases in world [ome­ga-6] con­sump­ti­on over the past cen­tury may be con­si­de­red a very lar­ge un­cont­rol­led ex­pe­ri­ment that may ha­ve cont­ri­bu­ted to inc­re­ased so­ci­etal bur­dens of ag­gres­si­on, dep­res­si­on, and car­di­ovas­cu­lar mor­ta­lity.”*

  Of all the chan­ges to our fo­od system that go un­der the he­ading “The Wes­tern Di­et,” the shift from a fo­od cha­in with gre­en plants at its ba­se to one ba­sed on se­eds may be the most far re­ac­hing of all. Nut­ri­ti­onal sci­en­tists fo­cus on dif­fe­rent nut­ri­ents-whet­her the prob­lem with mo­dern di­ets is too many re­fi­ned car­bohyd­ra­tes, not eno­ugh go­od fats, too many bad fats, or a de­fi­ci­ency of any num­ber of mic­ro­nut­ri­ents or too many to­tal ca­lo­ri­es. But at the ro­ot of all the­se bi­oc­he­mi­cal chan­ges is a sing­le eco­lo­gi­cal chan­ge. For the shift from le­aves to se­eds af­fects much mo­re than the le­vels of ome­ga-3 and ome­ga-6 in the body. It al­so helps ac­co­unt for the flo­od of re­fi­ned car­bohyd­ra­tes in the mo­dern di­et and the dro­ught of so many mic­ro­nut­ri­ents and the sur­fe­it of to­tal ca­lo­ri­es. From le­aves to se­eds: It’s al­most, if not qu­ite, a The­ory of Everyt­hing.

  5) From Food Culture to Food Science

  The last im­por­tant chan­ge wro­ught by the Wes­tern di­et is not, strictly spe­aking, eco­lo­gi­cal, at le­ast not in any nar­row sen­se of the word. But the in­dust­ri­ali­za­ti­on of our fo­od that we call the Wes­tern di­et is syste­ma­ti­cal­ly and de­li­be­ra­tely un­der­mi­ning tra­di­ti­onal fo­od cul­tu­res everyw­he­re. This may be as dest­ruc­ti­ve of our he­alth as any nut­ri­ti­onal de­fi­ci­ency.

  Be­fo­re the mo­dern fo­od era-and be­fo­re the ri­se of nut­ri­ti­onism-pe­op­le re­li­ed for gu­idan­ce abo­ut what to eat on the­ir na­ti­onal or eth­nic or re­gi­onal cul­tu­res. We think of cul­tu­re as a set of be­li­efs and prac­ti­ces to help me­di­ate our re­la­ti­ons­hip to ot­her pe­op­le, but of co­ur­se cul­tu­re-at le­ast be­fo­re the ri­se of mo­dern sci­en­ce-has al­so pla­yed a cri­ti­cal ro­le in hel­ping to me­di­ate pe­op­le’s re­la­ti­ons­hip to na­tu­re. Eating be­ing one of the most im­por­tant ma­ni­fes­ta­ti­ons of that re­la­ti­ons­hip, cul­tu­res ha­ve had a gre­at de­al to say abo­ut what and how and why and when and how much we sho­uld eat. Of co­ur­se when it co­mes to fo­od, cul­tu­re is anot­her word for mom, the fi­gu­re who typi­cal­ly pas­ses on the fo­od ways of the gro­up-fo­od ways that en­du­red, by the way, only be­ca­use they ten­ded to ke­ep pe­op­le he­althy.

  The she­er no­velty and gla­mo­ur of the Wes­tern di­et, with its se­ven­te­en tho­usand new fo­od pro­ducts every ye­ar and the mar­ke­ting po­wer-thirty-two bil­li­on dol­lars a ye­ar-used to sell us tho­se pro­ducts, has overw­hel­med the for­ce of tra­di­ti­on and left us whe­re we now find our­sel­ves: rel­ying on sci­en­ce and jo­ur­na­lism and go­vern­ment and mar­ke­ting to help us de­ci­de what to eat. Nut­ri­ti­onism, which aro­se to help us bet­ter de­al with the prob­lems of the Wes­tern di­et, has lar­gely be­en co-opted by it: used by the in­dustry to sell mo­re nut­ri­ti­onal­ly “enhan­ced” pro­ces­sed fo­od and to un­der­mi­ne furt­her the aut­ho­rity of tra­di­ti­onal fo­od cul­tu­res that stand in the way of fast fo­od. In­dustry gre­atly amp­li­fi­es the cla­ims of nut­ri­ti­onal sci­en­ce thro­ugh its ad­ver­ti­sing and, thro­ugh its spon­sors­hip of self-ser­ving nut­ri­ti­onal re­se­arch, cor­rupts it.* The pre­dic­tab­le re­sult is the ge­ne­ral ca­cop­hony of nut­ri­ti­onal in­for­ma­ti­on rin­ging in our ears and the wi­desp­re­ad con­fu­si­on that has co­me to sur­ro­und this most fun­da­men­tal of cre­atu­rely ac­ti­vi­ti­es: fin­ding so­met­hing go­od to eat.

  You wo­uld not ha­ve bo­ught this bo­ok and re­ad this far in­to it if yo­ur fo­od cul­tu­re was in­tact and he­althy. And whi­le it is true that most of us unt­hin­kingly pla­ce the aut­ho­rity of sci­en­ce abo­ve cul­tu­re in all mat­ters ha­ving to do with our he­alth, that pre­j­udi­ce sho­uld at le­ast be exa­mi­ned. The qu­es­ti­on we ne­ed to ask is, Are we bet­ter off with the­se new aut­ho­ri­ti­es tel­ling us how to eat than we we­re with the tra­di­ti­onal aut­ho­ri­ti­es they sup­plan­ted? The ans­wer by now sho­uld be cle­ar.

  It might be ar­gu­ed that at this po­int we sho­uld simply ac­cept that fast fo­od is our fo­od cul­tu­re and get on with it. Over ti­me, pe­op­le will get used to eating this way, and our he­alth will imp­ro­ve as we gra­du­al­ly adj­ust to the new fo­od en­vi­ron­ment. Al­so, as nut­ri­ti­onal sci­en­ce imp­ro­ves, we sho­uld be ab­le to ame­li­ora­te the wor
st ef­fects of this di­et. Al­re­ady fo­od sci­en­tists are fi­gu­ring out ways to mic­ro­en­cap­su­la­te ome­ga-3s and ba­ke them in­to our vi­ta­min-for­ti­fi­ed bre­ad. But I’m not su­re we sho­uld put our fa­ith in fo­od sci­en­ce, which so far has not ser­ved us very well, or in evo­lu­ti­on, eit­her.

  The­re are a co­up­le of prob­lems with trying simply to get used to the Wes­tern di­et. You co­uld ar­gue that, com­pa­red to the Abo­ri­gi­nes, say, or Inu­it, we are get­ting used to it-most of us don’t get qu­ite as fat or di­abe­tic as they do. But our “adj­ust­ment” lo­oks much less pla­usib­le when you con­si­der that, as men­ti­oned, fully a qu­ar­ter of all Ame­ri­cans suf­fer from me­ta­bo­lic syndro­me, two thirds of us are over­we­ight or obe­se, and di­et-re­la­ted di­se­ases are al­re­ady kil­ling the ma­j­ority of us. The con­cept of a chan­ging fo­od en­vi­ron­ment is not just a me­tap­hor; nor is the idea of adap­ting to it. In or­der for na­tu­ral se­lec­ti­on to help us adapt to the Wes­tern di­et, we’d ha­ve to be pre­pa­red to let tho­se whom it sic­kens die. Al­so, many of the chro­nic di­se­ases ca­used by the Wes­tern di­et co­me la­te in li­fe, af­ter the child­be­aring ye­ars, a pe­ri­od of our li­ves in which na­tu­ral se­lec­ti­on ta­kes no in­te­rest. Thus ge­nes pre­dis­po­sing pe­op­le to the­se con­di­ti­ons get pas­sed on rat­her than we­eded out.